Neonatal Fc Receptor The neonatal Fc receptor (FcRn) was initially identified as an immunoglobulin G (IgG) receptor in the intestinal epithelial cells of neonatal rodents (Simister and Rees, 1985 ) FcRn transports IgG from the maternal milk across the mucosal layer and releases it into blood of neonatal rodents to endow passive immunityThe neonatal fragment crystallizable (Fc) receptor (FcRn) is a multifunctional atypical Fcgamma receptor (FcγR) FcRn was initially identified as responsible for IgG transport from maternal to fetal circulation across the placenta, and later for IgG recyclingNeonatal Fc receptor is similar to these proteins Polymeric immunoglobulin receptor, CC chemokine receptor type 7, Smoothened and more
Pdf Fcrn The Neonatal Fc Receptor Comes Of Age Semantic Scholar
